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QSC Services

QSC Service Request Form: https://redcap.link/QSC_Project_Request_Form

Use this form if you have biostatistics, bioinformatics or informatics needs for your research project.

Note that some requests may take several weeks to complete.

Specific Expertise from QSC

To support research projects and cores, the QSC provides centralized statistical and bioinformatics services, one-on-one training, collaborative research and data management support for Partnership research projects and cores. QSC services include expertise in the following areas:

  1. ORIEN Avatar/TCC Molecular Data Requests
    • - Requesting data/numbers from TCC
    • - Access counts and availability of ORIEN Avatar molecular data from PRBB
  2. Biostatistics: Data science including basic statistical modeling, data cleaning, experimental design and power calculations
    • - Statistical experimental design support in cell line, animal study, and human behavioral intervention or clinical trial
    • - Grant Preparation (Rigor & Reproducibility)
    • - Calculate adequate sample sizes
    • - Perform statistical power calculations
    • - Design and execute randomization approaches
    • - Establish clearly defined outcomes/endpoints and relevant variables
    • - Assist in identifying appropriate statistical approaches (e.g. survival analysis, regression model, and mixed effect model)
  3. Informatics: Data processing, data integration and web-based systems development
    • - Software/database development
    • - HIPAA-compliant high-quality data collection
    • - Data integration
    • - Data sharing
    • - Data submission to public repositories
    • - Data access to public repositories (eg. dbGAP, TCGA)
    • - REDCap survey development
  4. Bioinformatics: Bioinformatics algorithms and computational biology focused on ‘omics technologies
    • - Genetic ancestry estimations (genome-wide or at a locus of interest)
    • - Next-gen DNA sequencing variant identification (germ-line and somatic)
    • - Variant annotation and classification
    • - RNA sequencing expression analysis
    • - RNA sequencing fusion detection
    • - Putative Neoantigen identification
    • - Microarray/public data analysis
    • - Gene annotation
    • - Single cell/spatial transcript omics
    • - Proteomics analysis
    • - Methylation array analysis
  5. Population Science Expertise
    • - Sample size/population determination
    • - Observational study design
    • - EWAS
    • - Admixture mapping
    • - Genetic association studies (subset of genes/genome wide)